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tapentadol Patients receiving other phenothiazines, sedative agents or other CNS depressants concomitantly with tapentadol may exhibit additive CNS depression .
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At equi-analgesic doses, tapentadol appears to have an improved gastrointestinal tolerability profile as well as lower rates of discontinuation as a result of side effects compared to tapentadol oxycodone .
tapentadol pharmacology tapentadol vs norco nucynta ir vs nucynta er tapentadol ingredients Conflict of interest: Dr V Mendis was a principal investigator for the open label phase III drug trial on tapentadol conducted by Grunenthal Ltd and has received funding for sitting on advisory boards, chairing the drug launch in Essex and giving talks for GPs .

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